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Comparator Trials

Meaning

Comparator Trials are a type of clinical study designed to evaluate the efficacy and safety of a new intervention or treatment protocol against an existing, established standard of care, rather than solely against a placebo. This design provides essential real-world context for assessing the relative clinical benefit and therapeutic index of novel hormonal or longevity treatments. The primary goal is to determine if the new strategy is non-inferior, superior, or simply an acceptable alternative to current best practices.