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Combined Hormone Therapy

Meaning

Combined Hormone Therapy (CHT) is a clinical strategy involving the simultaneous administration of two or more distinct hormones to address a complex endocrine deficiency or imbalance, often utilized in the management of menopausal symptoms or andropause. In women, this typically refers to the co-administration of estrogen and a progestogen to mitigate the risk of endometrial hyperplasia associated with unopposed estrogen. This therapeutic approach aims for a comprehensive restoration of physiological hormone balance.