A proactive and integrated clinical approach focused on optimizing the complex network of neurological and physiological processes that underpin mental capabilities like attention, memory, and executive function. This management strategy utilizes personalized diagnostics, including hormonal and metabolic profiling, to identify and address individual vulnerabilities that could compromise cognitive health. The goal is to maintain peak mental performance and build cognitive reserve against age-related decline.
Origin
This term is a clinical application of systems biology and cognitive science, emphasizing a holistic, engineering-like approach to brain health rather than simply treating symptoms. ‘Cognitive Systems’ refers to the interconnected functional units of the brain responsible for thought and perception. ‘Management’ highlights the ongoing, adaptive clinical oversight required to sustain optimal function over time.
Mechanism
Effective management involves modulating key biological regulators that impact neuronal function and connectivity. This includes the precise balancing of neurohormones, such as optimizing the ratio of glucocorticoids to mineralocorticoids, and ensuring adequate levels of neurotrophic factors. Interventions also target vascular health, as cerebral blood flow is critical for nutrient and oxygen delivery, and regulate inflammation, which can impair synaptic integrity. Regular, targeted assessments guide the dynamic adjustment of these biological parameters.
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