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Cognitive Receptor Sensitivity

Meaning

Cognitive Receptor Sensitivity refers to the responsiveness of neuronal hormone receptors in the central nervous system to circulating endocrine signals, directly impacting neuroplasticity, mood, and cognitive function. Optimal sensitivity ensures that even physiological hormone concentrations can effectively transmit signals within the brain, supporting healthy neural architecture and efficient information processing. Diminished sensitivity, often due to aging or chronic stress, can lead to cognitive decline despite adequate systemic hormone levels. This metric is a crucial determinant of hormonal efficacy in the brain.