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Cognitive Persistence

Meaning

Cognitive Persistence refers to the sustained capacity of the brain to maintain focus, execute complex tasks, and resist mental fatigue over extended periods. This executive function is fundamentally supported by optimal neurochemical and hormonal balance, making it a key metric in hormonal health. Impairment in cognitive persistence is often an early clinical sign of hormonal dysregulation, such as thyroid imbalance, cortisol excess, or declining sex steroid levels. Improving this function is a critical therapeutic goal for enhancing both productivity and quality of life.