A Cognitive Longevity Strategy is a structured, multi-modal plan designed to preserve and enhance neurocognitive function across the entire lifespan, aiming for sustained mental acuity into advanced age. This strategy integrates neuroprotective hormonal optimization with targeted lifestyle adjustments to support synaptic health. It is a proactive framework for maintaining executive function and memory consolidation.
Origin
This strategy merges concepts from the field of geroscience, which studies the biology of aging, with applied clinical neuroscience. The ‘longevity’ aspect points toward extending the healthspan, while ‘strategy’ implies a deliberate, evidence-based clinical roadmap. It represents a shift from reactive treatment of cognitive decline to preemptive structural support.
Mechanism
The underlying mechanism involves fostering neurogenesis and synaptogenesis by supporting trophic factors like BDNF, often influenced by systemic hormonal balance. Furthermore, strategies aim to reduce oxidative stress and maintain cerebral vascular integrity, which are crucial for efficient neuronal communication. Proper management of systemic inflammation directly impacts the microenvironment necessary for long-term cognitive maintenance.
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