Cognitive Hormone Linkage defines the intricate, bidirectional communication system between the central nervous system’s executive functions and the circulating concentrations of various endocrine signals. This linkage explains how shifts in hormones directly affect mood, memory consolidation, and executive processing speed. Understanding this connection is essential for addressing age-related cognitive decline. The fidelity of this linkage determines mental sharpness.
Origin
This concept arises from the integration of cognitive psychology and endocrinology, focusing on the chemical messengers that influence neural plasticity and neurotransmitter balance. It acknowledges that the brain is both a producer and a target of hormonal influence. The linkage highlights a sophisticated system of internal regulation.
Mechanism
Key hormones like DHEA-S, estrogen, and cortisol interact with neural receptors, modulating synaptic strength and neuronal excitability. For example, adequate estrogen supports hippocampal neurogenesis crucial for memory encoding. Furthermore, proper thyroid hormone action is required to maintain the metabolic rate necessary for rapid neuronal firing.
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