Quantifiable physiological, biochemical, or structural markers that exhibit a statistically significant relationship with specific domains of mental processing, such as memory, attention, executive function, and processing speed. These correlates serve as objective indicators of neurocognitive health, moving beyond subjective assessment alone. Hormonal status, cerebral blood flow, and neurotrophic factor levels are examples of critical biological correlates.
Origin
This concept emerges from the interdisciplinary fields of cognitive neuroscience, psychoneuroendocrinology, and clinical psychology, seeking to bridge the gap between subjective mental experience and measurable biological phenomena. The search for reliable ‘correlates’ is fundamental to developing effective interventions for age-related cognitive decline and neurodegenerative conditions.
Mechanism
The correlation is often mediated by the action of neurosteroids and classic endocrine hormones on neuronal plasticity and synaptic transmission within the central nervous system. For instance, optimal levels of thyroid hormone and testosterone are essential for maintaining hippocampal structure and function, which correlates strongly with memory consolidation. Furthermore, cerebral glucose metabolism, a bioenergetic correlate, directly influences the brain’s capacity for complex thought processes and sustained attention.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.