The clinical outcome of mitigating the subjective feeling of mental exhaustion or reduced cognitive performance, often linked to HPA axis dysfunction or suboptimal neuroendocrine support. We aim to restore the efficiency of neural networks responsible for sustained attention and executive function. This improvement directly correlates with optimized systemic vitality.
Origin
This concept bridges neuropsychology with clinical endocrinology, focusing on the mental aspect of well-being often compromised by chronic physiological imbalance. Reduction implies an active intervention to shift the neurochemical state away from fatigue toward alertness. It addresses the patient’s subjective experience of mental capacity.
Mechanism
Reduction is achieved by stabilizing key neurotransmitter systems, particularly those modulated by stress hormones like cortisol, and ensuring adequate precursor availability for synthesis. Optimal thyroid hormone status and balanced sex hormone levels are crucial co-factors supporting neuronal energy metabolism. Improving mitochondrial respiration efficiency within neural tissue directly translates to enhanced capacity for sustained cognitive effort.
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