A category of pharmacological agents, nutraceuticals, or endogenous substances specifically utilized to improve executive functions of the brain, including memory, focus, motivation, and mental clarity. These compounds are clinically applied to support neuroplasticity and mitigate age-related cognitive decline, aiming to optimize the brain’s processing efficiency. Their use is part of a holistic approach to maintaining neurobiological vitality throughout the lifespan.
Origin
The concept stems from neuropsychopharmacology and traditional medicine, with the modern term evolving alongside the development of nootropics and smart drugs. “Cognitive Enhancement” reflects the goal of moving beyond baseline function to an optimized state, focusing on measurable improvements in mental performance. The designation “Compounds” is a broad classification covering both synthetic pharmaceuticals and natural bioactives.
Mechanism
These compounds exert their effects primarily by modulating neurotransmitter systems, such as increasing acetylcholine availability for memory or dopamine and norepinephrine for focus and motivation. Many also work by enhancing cerebral blood flow, ensuring optimal oxygen and nutrient delivery to active brain regions. Furthermore, some compounds support mitochondrial function within neurons, thereby improving the overall energy status and resilience of brain cells against oxidative stress.
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