The measurable capacity for sustained, high-level executive function, including focus, working memory, and mental processing speed, supported by adequate cerebral energy substrates. This state reflects the efficiency of neuronal energy metabolism, heavily influenced by glucose regulation and thyroid hormone action in the CNS. It is a critical output of overall systemic metabolic health.
Origin
This term arises from cognitive neuroscience and functional endocrinology, recognizing that mental performance is directly dependent on brain energy supply and neurochemical balance. It moves beyond subjective alertness to quantify the brain’s metabolic reserve for complex tasks. The concept bridges neurobiology with the regulation of systemic fuel sources.
Mechanism
Cognitive Energy is sustained through efficient cerebral glucose uptake and subsequent mitochondrial ATP generation within neurons and glial cells. Thyroid hormones are crucial for regulating the expression of glucose transporters and metabolic enzymes in the brain. Furthermore, balanced cortisol levels ensure the availability of substrates necessary for peak neural activity without inducing excitotoxicity.
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