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Cognitive Energetics

Meaning

Cognitive energetics describes the complex metabolic processes and energy substrate utilization that underpin high-level brain functions, including attention, memory, and executive control. This concept moves beyond mere structural integrity to focus on the dynamic energy demands of neuronal and glial cells, particularly the regulation of glucose metabolism and mitochondrial efficiency. Disruptions in cognitive energetics are clinically implicated in conditions like metabolic syndrome, neurodegenerative disorders, and states of hormonal imbalance, such as hypo- or hyperthyroidism. Optimizing brain fuel utilization is a therapeutic target for enhancing mental performance and resilience.