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Cognitive Co-Factors

Meaning

Cognitive co-factors are essential micronutrients, vitamins, minerals, and endogenous compounds that are metabolically required for optimal brain function, particularly those processes underpinning attention, memory, and executive function. These factors are not the primary signaling molecules themselves but are necessary participants in enzymatic reactions and structural maintenance of neuronal and glial cells. Their adequate supply is critical for the synthesis of neurotransmitters and the maintenance of synaptic plasticity. Deficiencies in these co-factors can significantly impair cognitive performance and hormonal signaling.