The clinical process of employing targeted interventions, including hormonal, nutritional, and lifestyle adjustments, to reverse deficits in executive function, memory, attention, and processing speed. This restoration addresses the neuroendocrine and metabolic factors that contribute to mental fogginess and cognitive decline. The ultimate goal is to optimize neural efficiency and enhance overall brain performance.
Origin
This therapeutic concept arises from the growing clinical evidence linking hormonal imbalances, mitochondrial dysfunction, and chronic inflammation to cognitive impairment, particularly in aging populations. It integrates findings from neuroendocrinology and functional neurology to create a multi-faceted approach to brain health. The term emphasizes a return to an optimal, prior state of function.
Mechanism
Restoration typically involves optimizing neurosteroid levels, such as pregnenolone and DHEA, which act as neurotrophic agents and influence neurotransmitter synthesis. Interventions also target improved cerebral blood flow, reduction of neuroinflammation through cytokine modulation, and enhancement of mitochondrial ATP production within neuronal cells. This combined mechanism supports synaptic plasticity and neuronal network integrity essential for clear thought processes.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.