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Clomiphene Citrate Protocol

Meaning

The Clomiphene Citrate Protocol is a structured clinical regimen involving the cyclical administration of the selective estrogen receptor modulator (SERM), Clomiphene Citrate, primarily utilized to modulate and stimulate the hypothalamic-pituitary-gonadal (HPG) axis. In male patients, this protocol is frequently employed to treat secondary hypogonadism by increasing endogenous testosterone production while maintaining spermatogenesis. For female patients, it serves as a common, first-line intervention to induce ovulation in cases of anovulatory infertility. The protocol requires precise dosing and careful endocrine monitoring to optimize the hormonal response and ensure a favorable therapeutic outcome.