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Clomiphene Citrate in Men

Meaning

Clomiphene Citrate, primarily known as a Selective Estrogen Receptor Modulator (SERM), is utilized clinically in men to treat secondary hypogonadism by stimulating endogenous testosterone production. This pharmacological intervention offers an alternative to exogenous testosterone replacement, particularly when preserving fertility is a priority. The treatment aims to elevate serum testosterone levels while maintaining or improving the patient’s sperm count and function. Clinical oversight is essential to monitor the pituitary-gonadal axis response and manage potential side effects.