The evidence-based use of short-chain amino acid sequences, or peptides, administered therapeutically to modulate specific physiological pathways relevant to health, recovery, or hormone modulation. This application requires precise dosing and understanding of the peptide’s target receptor affinity and half-life within the patient. It represents an advanced area of therapeutic intervention.
Origin
Peptides are derived from the Greek peptos, meaning “digested,” referring to their fundamental structure as chains of amino acids. Clinical application denotes their transition from laboratory research into structured patient care modalities.
Mechanism
Peptides function by mimicking or antagonizing the action of endogenous signaling molecules, often binding to specific cell surface receptors to trigger intracellular cascades. For instance, growth hormone-releasing peptides stimulate the pituitary gland to increase pulsatile growth hormone secretion. The mechanism is highly specific, often involving receptor selectivity to minimize off-target effects compared to broad-acting hormones.
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