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Clinical Evidence Gaps

Meaning

Clinical Evidence Gaps represent areas within medical practice where insufficient high-quality, randomized controlled trial data or robust observational studies exist to definitively guide clinical decision-making. These gaps highlight uncertainties in the efficacy, safety, or optimal dosing of interventions, particularly for novel or highly personalized therapies like compounded hormonal regimens. Identifying these lacunae is essential for prioritizing future research and ensuring the continuous progression toward evidence-based patient care.