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Circuit Integration Timelines

Meaning

Circuit integration timelines refer to the duration required for newly generated neurons or modified synaptic connections to become functionally incorporated into existing neural networks within the central nervous system. This concept is particularly relevant in the context of adult hippocampal neurogenesis, where progenitor cells must mature and establish stable, functional connections. The speed and success of this integration are critical determinants of cognitive function, especially in learning and memory. These timelines are highly sensitive to systemic factors, including hormonal status and metabolic health.