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Circadian Rhythm Re-Regulation

Meaning

The clinical process of systematically restoring the natural, approximately 24-hour cycle of physiological and behavioral processes that govern sleep-wake cycles, hormone secretion, metabolic activity, and core body temperature. Re-regulation aims to re-establish the optimal phase relationship between the central pacemaker in the suprachiasmatic nucleus (SCN) and peripheral cellular oscillators. Achieving this synchronization is crucial for metabolic health, cognitive function, and the efficiency of endocrine signaling. Chronic desynchronization is a known contributor to disease and accelerated aging.