Circadian Rhythm and Hormones describes the profound interaction where the body’s intrinsic 24-hour oscillation system dictates the timing, amplitude, and pattern of nearly all endocrine secretions. Optimal physiological function depends on the alignment between environmental cues and these hormonal pulses. Disruption leads to systemic dysregulation.
Origin
This understanding stems from chronobiology, recognizing the suprachiasmatic nucleus (SCN) as the master pacemaker that coordinates peripheral oscillators throughout the body. The connection to endocrinology became clear when observing the rhythmic release of hormones like cortisol and growth hormone. Proper alignment is essential for metabolic health.
Mechanism
The SCN receives photic input, synchronizing its rhythm, which then projects signals to influence hormone-secreting glands. For example, light suppression of melatonin secretion dictates the onset of the active phase, during which cortisol levels naturally peak to support alertness and energy mobilization. Maintaining this rhythm ensures hormones are present when target tissues exhibit peak receptor sensitivity.
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