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Circadian Phenotype Correction

Meaning

This clinical strategy involves therapeutic interventions designed to re-establish the proper phase and amplitude of an individual’s endogenous circadian rhythms when they have become dysregulated. The goal is to align the internal biological timing (the chronotype) with the external light-dark and social cycles, thereby restoring optimal hormonal and metabolic function. Correction often targets the master clock in the brain and its downstream effectors, improving sleep quality and daytime vigilance. It represents a personalized approach to treating rhythm disorders beyond simple symptom management.