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Circadian Desynchronization Effects

Meaning

Circadian desynchronization effects describe the adverse physiological and behavioral consequences resulting from a misalignment between the body’s internal circadian rhythm and external environmental or behavioral cycles. This discordance disrupts the precise 24-hour timing of numerous biological functions, including hormonal pulses, metabolic enzyme activity, and cell cycle regulation. Clinically, this state is associated with an increased risk for chronic diseases, such as metabolic syndrome, cardiovascular issues, and mood disorders. Shift work and inconsistent sleep patterns are common contributors to this systemic timing error.