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Circadian Calibration

Meaning

Circadian Calibration refers to the precise synchronization of the body’s endogenous biological rhythms, governed by the master suprachiasmatic nucleus (SCN) in the hypothalamus, with the external 24-hour light-dark and social cycles. This process is essential for maintaining optimal hormonal balance, metabolic efficiency, and sleep-wake architecture. Effective calibration ensures that the daily ebb and flow of physiological processes are correctly timed to the environment, supporting systemic health and longevity.