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Chronology of Biological Effect

Meaning

This concept describes the predictable temporal sequence in which a physiological or pharmacological intervention manifests its observable effects within the human body, from the initial molecular binding to the final clinical outcome. It involves mapping the time course of action, encompassing the immediate cellular response, intermediate pathway modulation, and the delayed, cumulative tissue-level changes. Understanding this chronology is essential for designing effective treatment protocols and managing patient expectations in clinical practice.