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Chronological Time Variance

Meaning

Chronological Time Variance describes the clinical observation that an individual’s biological age and overall health status can deviate significantly from their actual calendar age. This variance reflects the cumulative impact of lifestyle choices, genetics, and environmental exposures on physiological reserve and the rate of cellular aging. In the hormonal domain, this variance manifests as endocrine system function that is either accelerated or decelerated relative to expected age-matched norms. Clinically, minimizing negative variance is a key goal of longevity protocols.