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Chronological Senescence Mitigation

Meaning

Chronological Senescence Mitigation represents a clinical strategy aimed at slowing or reversing the biological changes associated with the passage of time, distinct from pathological aging. This involves targeted interventions that address the hallmarks of aging at a molecular and cellular level, such as telomere shortening, epigenetic alterations, and cellular exhaustion. The ultimate goal is to extend the period of healthspan, ensuring vitality and functional capacity well into later life. It shifts the focus from merely treating age-related disease to actively promoting biological resilience.