Skip to main content

Chronological Decoupling

Meaning

Chronological Decoupling is the scientific and clinical phenomenon where an individual’s biological age, as determined by validated biomarkers like telomere length or epigenetic clocks, is significantly younger than their chronological age. This decoupling represents a successful intervention against the natural progression of senescence, indicating a state of enhanced healthspan and cellular vitality. Achieving this state is a core objective in preventative and longevity medicine, suggesting that the rate of physiological decline has been measurably slowed.