The deliberate and precise adjustment of an individual’s daily behavioral and environmental inputs to align the internal circadian rhythms with external cues and optimal physiological timing. This practice aims to harmonize the central pacemaker in the suprachiasmatic nucleus with peripheral clocks for improved hormonal signaling and metabolic health.
Origin
The term combines ‘chronobiology,’ the study of biological rhythms, with ‘tuning,’ implying a fine-adjustment for peak performance, similar to tuning an instrument. It represents a clinical application of circadian science in wellness and longevity protocols.
Mechanism
Tuning involves strategically timing exposure to light, meal consumption, exercise, and sleep to reinforce the desired phase of the circadian rhythm. Specific light exposure, particularly bright light upon waking, helps to suppress melatonin and phase-advance the clock, while avoiding blue light exposure in the evening facilitates the natural melatonin rise, thereby supporting robust hormonal cycles and energy regulation.
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