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Chronic Pathogen Defense

Meaning

Chronic Pathogen Defense refers to the sustained, complex immunological and physiological responses the body mounts against persistent or latent infectious agents that evade immediate clearance. This state of low-grade, long-term immune activation often involves continuous resource allocation, which can deplete systemic reserves and contribute to chronic inflammatory states. Effective defense requires balancing the eradication effort with the preservation of host tissue integrity, a process heavily influenced by neuroendocrine regulation. Managing this defense is critical in hormonal health, as chronic immune stress profoundly impacts adrenal and thyroid function.