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Chronic Injury Resolution

Meaning

Chronic Injury Resolution is the clinical objective of systematically terminating the persistent, low-grade inflammatory and non-healing state characteristic of chronic tissue damage or senescence. This process moves beyond temporary symptom management to actively dismantle the biological drivers that perpetuate chronic inflammation and impede regenerative processes. Achieving resolution involves restoring normal tissue homeostasis and eliminating cellular debris and senescent cells that contribute to the inflammatory microenvironment. Successful resolution is a critical step in restoring long-term functional integrity to affected tissues.