Skip to main content

Chronic Fatigue Etiology

Meaning

Chronic Fatigue Etiology is the study and identification of the specific underlying causes and pathogenic mechanisms contributing to the clinical syndrome of chronic, debilitating fatigue that is not relieved by rest. In the context of hormonal health, the etiology often involves dysregulation of the Hypothalamic-Pituitary-Adrenal (HPA) axis, subtle thyroid dysfunction, or mitochondrial energy production deficits. Pinpointing the etiology is the essential first step toward developing a targeted and effective clinical intervention.