Skip to main content

Chronic Fatigue

Meaning

Chronic fatigue, in a clinical context, is characterized by a persistent, relapsing, or disproportionate sense of exhaustion that is not substantially alleviated by rest. This profound weariness significantly impacts daily function and persists for an extended period, typically six months or more. It is a symptom frequently observed in the hormonal health space, often correlating with dysregulation of the HPA axis and subsequent cortisol pattern disturbances. Differentiating this from transient tiredness is critical, as chronic fatigue often involves underlying physiological disturbances beyond simple lack of sleep. Clinicians must investigate potential endocrinological, immunological, and metabolic etiologies to establish a precise diagnosis and effective management plan.