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Cholinergic Co-Transmission

Meaning

Cholinergic Co-Transmission describes the sophisticated neurobiological phenomenon where a single presynaptic neuron releases acetylcholine (ACh) simultaneously alongside one or more distinct, non-cholinergic signaling molecules. This mechanism significantly expands the communication repertoire of the nervous system, allowing for the fine-tuning and differential modulation of postsynaptic target cells. It is a fundamental concept in autonomic and central nervous system function, providing a layered control over physiological responses. This complex signaling ensures precise control of target organs.