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Choline Deficiency

Meaning

Choline deficiency represents an insufficient systemic level of the essential nutrient choline, which is vital for phospholipid synthesis, cell membrane integrity, and the production of the neurotransmitter acetylcholine. Within the hormonal health domain, this deficiency compromises the structural integrity of endocrine cell membranes, potentially impairing receptor function and signal transduction. Inadequate choline intake can contribute to non-alcoholic fatty liver disease, which is a state of significant metabolic and hormonal dysregulation. This nutritional deficit can profoundly impact the synthesis and release of key signaling molecules.