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Chemosensitive Response

Meaning

A chemosensitive response is the measurable, positive biological reaction of a cell population, tissue, or malignant tumor to the direct administration of a specific chemical compound, most often a cytotoxic chemotherapeutic agent. Clinically, this term indicates that a particular disease, such as a hormone-dependent neoplasm, is demonstrably susceptible to treatment with a chosen drug regimen. The favorable response is typically quantified by objective metrics, including a significant reduction in tumor burden, a decrease in relevant disease biomarkers, or a prolonged stabilization of the disease state.