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Chemical Signaling Fidelity

Meaning

Chemical Signaling Fidelity is a measure of the accuracy and reliability with which endogenous chemical messengers, such as hormones and neurotransmitters, transmit their information to target cells and elicit the appropriate physiological response. High fidelity indicates precise binding and downstream effect, while reduced fidelity suggests impaired receptor sensitivity or altered signal transduction pathways, a common feature of aging and chronic disease. Maintaining this fidelity is crucial for optimal endocrine and neurological function.