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Chemical Shielding Capacity

Meaning

Chemical Shielding Capacity quantifies the body’s inherent ability to neutralize, detoxify, and safely excrete harmful endogenous or exogenous chemical compounds, including metabolic byproducts and environmental toxins. This protective metric reflects the functional reserve of key detoxification pathways, particularly those involving hepatic Phase I and Phase II enzymes. A robust capacity is crucial for maintaining hormonal integrity, as many hormones and their metabolites require efficient clearance. Diminished shielding capacity can lead to accumulation of toxic intermediates, negatively impacting endocrine signaling and cellular health.