The physiological process where endogenous chemical messengers, predominantly neurotransmitters, neuropeptides, and circulating hormones, modulate the complex neural circuits that underlie all aspects of cognition, emotion, and conscious experience. This regulation dictates mood stability, attentional capacity, and information processing speed.
Origin
This concept merges the disciplines of neurochemistry, endocrinology, and cognitive neuroscience, recognizing that mental states are direct outputs of chemical signaling within the central nervous system. It acknowledges the profound influence of the endocrine system on brain function, a key tenet of hormonal health.
Mechanism
Steroid hormones, for example, cross the blood-brain barrier to bind to nuclear receptors, altering gene expression for neurotransmitter synthesis and receptor density, thus modulating synaptic plasticity. Furthermore, circulating peptides like ghrelin and leptin influence hypothalamic circuits, indirectly impacting cognitive resource allocation and executive control through their systemic metabolic signals.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.