A systematic clinical and lifestyle approach designed to minimize an individual’s intake and absorption of exogenous chemical compounds that can negatively impact biological function. The protocol encompasses dietary choices, filtration of water and air, and the careful selection of personal care and household products. Adherence to this protocol aims to reduce the body’s xenobiotic load and optimize hormonal signaling.
Origin
The necessity for such protocols arose from the convergence of environmental toxicology data and the clinical observation of chemically sensitive individuals. It is rooted in the preventive medicine principle that reducing upstream toxic input is essential for downstream physiological restoration.
Mechanism
By rigorously controlling external chemical exposure, the protocol reduces the substrate load on the hepatic cytochrome P450 enzyme systems, allowing them to function more efficiently on endogenous and unavoidable toxins. This lessened burden supports the liver’s capacity to properly conjugate and excrete steroid hormone metabolites, such as estrogens, thereby promoting hormonal balance and reducing the risk of metabolite-driven pathologies.
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