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Chemical Mixture Effects

Meaning

Chemical Mixture Effects refer to the complex biological outcomes that arise from simultaneous exposure to multiple chemical substances, even when each substance is present at a concentration below its individually established “no-observed-adverse-effect-level.” This phenomenon is highly relevant in hormonal health, as various endocrine-disrupting chemicals (EDCs) can interact additively, synergistically, or antagonistically to produce a cumulative effect on the endocrine system. Clinically, understanding these interactions is crucial for accurate risk assessment and intervention planning.