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Chain of Causation

Meaning

The chronological and logical sequence of events or factors that link an initial physiological trigger or pathology to a subsequent clinical outcome or hormonal dysfunction. In endocrinology, identifying this chain is crucial for determining the root cause of an imbalance, moving beyond mere symptom management. This diagnostic framework helps delineate how one hormonal or metabolic abnormality leads to the next, creating a cascade effect. Understanding the entire sequence allows for targeted, effective therapeutic intervention.