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Central Hypogonadism Assessment

Meaning

A comprehensive clinical and biochemical evaluation designed to confirm a diagnosis of secondary or tertiary hypogonadism, where the primary defect lies in the hypothalamus or pituitary gland. This assessment differentiates central causes from primary gonadal failure by analyzing the pituitary gonadotropins, Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH), in conjunction with gonadal steroid levels. The diagnostic process is crucial for determining the appropriate therapeutic intervention, such as clomiphene citrate or gonadotropin therapy.