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Central Autonomic Network

Meaning

The Central Autonomic Network (CAN) is a distributed collection of interconnected brain regions that collectively regulate the autonomic nervous system’s control over visceral function and emotional state. This network includes key structures like the hypothalamus, amygdala, and brainstem nuclei, serving as the interface between higher-level cognitive and emotional processing and the body’s physiological systems. It is the master coordinator for internal equilibrium, integrating signals to maintain cardiovascular, respiratory, and endocrine homeostasis. Dysregulation within the CAN is strongly implicated in stress-related hormonal disorders.