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Cellular Signaling Plasticity

Meaning

Cellular Signaling Plasticity is the inherent, adaptive ability of a biological cell to dynamically alter the responsiveness, magnitude, and pathway utilization of its internal communication networks in direct response to external stimuli or intrinsic metabolic changes. This profound adaptability is critical for maintaining systemic homeostasis and for executing complex, nuanced physiological responses, such as tissue regeneration or metabolic adaptation to caloric restriction. A measurable decline in this plasticity is often closely associated with the progression of chronic disease states and the biological aging process.