Skip to main content

Cellular Senescence Reduction Strategies

Meaning

Cellular Senescence Reduction Strategies are a collection of therapeutic and lifestyle interventions aimed at decreasing the burden of senescent cells, often termed “zombie cells,” within tissues. Senescent cells cease dividing but remain metabolically active, secreting a pro-inflammatory senescence-associated secretory phenotype (SASP) that drives tissue dysfunction and aging. Reducing this cellular load is a core focus of longevity and regenerative medicine. These strategies are vital for mitigating chronic inflammation and preserving tissue function.