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Cellular Response Sensitivity

Meaning

Cellular Response Sensitivity is a measure of how effectively a target cell detects and translates an external chemical signal, such as a hormone or growth factor, into a meaningful intracellular action. This sensitivity is a critical determinant of endocrine health, as it dictates the biological efficacy of circulating hormones, independent of their absolute concentration. Diminished sensitivity, often termed ‘resistance,’ can lead to systemic dysfunction, even when hormone levels appear normal. Optimizing this responsiveness is a key goal in precision hormonal therapy and longevity medicine.