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Cellular Response Fidelity

Meaning

Cellular Response Fidelity refers to the accuracy and reliability with which a target cell executes the biological instruction conveyed by a signaling molecule, such as a hormone or growth factor. High fidelity ensures that the cellular output precisely matches the endocrine input, leading to predictable and appropriate physiological outcomes. Loss of fidelity, often seen with age or disease, results in blunted or erroneous cellular reactions, compromising tissue function and systemic hormonal balance. This precision is essential for maintaining the intricate homeostatic mechanisms of the body.