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Cellular Renewal Chronology

Meaning

The precise, time-dependent sequence and regulation of biological processes involved in replacing damaged or aged cells and cellular components with new, functional ones across various tissues and organ systems. This concept integrates the study of circadian rhythms, hormonal cycles, and intrinsic cellular clocks, such as telomere shortening, to understand the optimal timing of repair and regeneration. It is a critical determinant of tissue health, functional reserve, and an individual’s biological age.