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Cellular Receptor Upregulation

Meaning

Cellular receptor upregulation refers to an increase in the number of specific receptors on a cell’s surface or within its cytoplasm, or an enhancement of their binding affinity, leading to an amplified cellular response to a particular ligand, such as a hormone or neurotransmitter. This adaptive process allows cells to become more sensitive to circulating signals, even when ligand concentrations are low, ensuring robust physiological responses.